产品详情

Chicken polyclonal antibody to Prostatic Acid Phosphatase
Host：Gallus
Reacts With：Human,Mouse,Rat
Immunogen：
Tested Applications：ICC,IF,IHC-P,WB
Application Dilutions：WB: 1:1000-2000, IHC-P: 1:500-1000
Application Notes：Recombinant mouse PAP protein was expressed using a baculoviral-delivery system. Antibodies against this protein were prepared by injecting purified recombinant PAP into laying hens, and purifying the IgY fraction from eggs collected from hyper-immunized hens.Experiment Notes: Mouse PAP is a 43,698 dalton protein (381 amino acids; NCBI accession numberAAF23171) associated with prostatic cancer cells, as well as primary afferent sensory neurons involved in the pain pathway. This protein is an enzyme that dephosphorylates adenosine monophosphate (AMP) in the dorsal horn gray matter of the spinal cord, generating free adenosine. Injections of PAP into the dorsal horn of experimental mice has been shown to decrease pain perception by acting in an antinociceptive, antihyperalgesic, and antiallodynic fashion.
Conjugation：Unconjugated
Clonality：